Co-infection between tuberculosis and malaria: A consideration on interaction of molecules and pathogenesis.

Human immunodeficiency virus (HIV) infection/ acquired immunodeficiency syndrome (AIDS) and malaria are counted as worst diseases for the following: (i) together cause 4 million deaths every year; and (ii) pregnant women are at high risk of developing anaemia and infection of placenta1. Children born to co-infected mother are in low birth weight. AIDS may increase the risk of severe malaria and antimalarial drugs are less effective1. Virus that cause AIDS replicate more readily. A common infection in a patient with AIDS is tuberculosis.